Dr. Jie Chen

Dr. Jie Chen
Jie Chen, Ph.D.
Postdoctoral Fellow
State Key Laboratory of Silkworm Genome Biology
Institute of Sericulture and Systems Biology, Southwest University
Email: cjswu826@163.com, jchen@swu.edu.cn
Phone: +86-23-68251088
Fex: +86-23-68251128


  • 2014   Postdoc  State Key Laboratory of Silkworm Genome Biology, Institute of Sericulture and Systems Biology, Southwest University, China.
  • 2011-2014   Ph.D.  Biochemistry and Molecular Biology (Supervisor: Prof. Zeyang Zhou), Institute of Sericulture and Systems Biology, Southwest University, China.
  • 2009-2011   M.S.  Microbiology (Supervisor: Prof. Zeyang Zhou), Institute of Sericulture and Systems Biology, Southwest University, China.
  • 2005-2009   B.Sc.  Biotechnology, College of Biotechnology, Southwest University, China.
  • 2006-2008   B.Sc. Administration Management, College of Political Science and Public Administration, Southwest University, China.

  • How do Microsporidia invade cells?
  • How is the spore wall built?
  • Who is responsible for inducing cell aggregation while microsporidia infection?
  • Vesicle trafficking in Microsporidia.


  1. Chen J, Geng L, Long M, Li T, Li Z, Yang D, Ma C, Wu H, Ma Z, Li C, Pan G, Zhou Z. Identification of a novel chitin-binding spore wall protein (NbSWP12) with a BAR-2 domain from Nosema bombycis (microsporidia). Parasitology. 2013, 140(11): 1394-402.
  2. Liu T, Xu J, Luo B, Chen J, Li Z, Li T, Pan G, Li X, Zhou Z. Nosema sp. PM-1, a new isolate of microsporidian from infected Papilio machaon Linnaeus, based on ultrastructure and molecular identification. 2015, Acta Parasitol. 60(2):330-6.
  3. Yang D, Pan G, Dang X, Shi Y, Li C, Peng P, Luo B, Bian M, Song Y, Ma C, Chen J, Ma Z, Geng L, Li Z, Tian R, Wei C, Zhou Z. Interaction and assembly of two novel proteins in the spore wall of the microsporidian species Nosema bombycis and their roles in adherence to and infection of host cells. Infect Immun. 2015, 83(4):1715-31
  4. Yang D, Dang X, Tian R, Long M, Li C, Li T, Chen J, Li Z, Pan G, Zhou Z. Development of an approach to analyze the interaction between Nosema bombycis (microsporidia) deproteinated chitin spore coats and spore wall proteins. J Invertebr Pathol. 2014, 115:1-7.
  5. Qiao L, Xiong G, Wang RX, He SZ, Chen J, Tong XL, Hu H, Li CL, Gai TT, Xin YQ, Liu XF, Chen B, Xiang ZH, Lu C, Dai FY. Mutation of a cuticular protein, BmorCPR2, alters larval body shape and adaptability in silkworm, Bombyx mori. Genetics. 2014, 196(4):1103-15.
  6. Zhengang Ma, Chunfeng Li, Guoqing Pan, Zhihong Li, Bing Han, Jinshan Xu, Xiqian Lan, Jie Chen, Donglin Yang, Quanmei Chen, Qi Sang, Xiaocun Ji, Tian Li, Mengxian Long, Zeyang Zhou. 2013. Genome-wide transcriptional response of silkworm (Bombyx mori) to infection by the microsporidian Nosema bombycis. PloS ONE. 2013, 8(12): e84137.
  7. Lin L, Pan G, Li T, Dang X, Deng Y, Ma C, Chen J, Luo J, Zhou Z. The protein import pore Tom40 in the Microsporidian Nosema bombycis. J Eukaryot Microbiol. 2012, 59(3):251-257.
  8. Zhi Li, Guoqing Pan, Tian Li, Wei Huang, Jie Chen, Lina Geng, Donglin Yang, Linling Wang, Zeyang Zhou. SWP5, A Novel Spore Wall Protein Interaction with Polar Tube in the Parasite Nosema bombycis (Microsporidia). Eukaryotic Cell. 2011, 11: 229-237.
  9. MA Qiang, DANG Xiaoqun, WANG Ying, CHEN Jie, LIU Fangyan, ZHAO Lifang, CAO Chenfu, Lǚ Jianqiang, PAN Guoqing, ZHOU Zeyang. Infectivity Variation of Nosema bombycis to Bombyx mori Embryonic Cells Under Different Cryopreservation Treatments. Science of Sericulture. 2014,40( 6) : 1055-1061. (In Chinese).
  10. LONG Mengxian, WU Yujiao, CHEN Jie, PAN Guoqing, LI Chunfeng, LI Tian, CHEN Guo, ZHOU Zeyang. Research Progress in Polar Tube Proteins of Microsporidia. Science of Sericulture. 2014,40( 5) : 0917-0923. (In Chinese).
  11. WU Yujiao, LONG Mengxian, CHEN Jie, LI Zhi, LI Zhihong, PAN Guoqing, LI Tian, ZHOU Zeyang. Cloning and Prokaryotic Expression of Nosema bombycis Polar Tube Protein 1 ( NbPTP1). Science of Sericulture. 2014,40( 2) : 0258-0264. (In Chinese).

  • China Postdoctoral Science Foundation Grant (2015M570763) 2015 – 2016
  • Fundamental Research Funds for the Central Universities (XDJK2015C004) 2015 – 2016
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